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Recent Publications


Gene-Targeted Mice with the Human Troponin T R141W Mutation Develop Dilated Cardiomyopathy with Calcium Desensitization.
Ramratnam M, Salama G, Sharma RK, Wang DW, Smith SH, Banerjee SK, Huang XN, Gifford LM, Pruce ML, Gabris BE, Saba S, Shroff SG, Ahmad F.
PloS one. 2016; 11(12):e0167681.
PMID: 27936050 


Malignant effects of multiple rare variants in sarcomere genes on the prognosis of patients with hypertrophic cardiomyopathy.
Wang J, Wang Y, Zou Y, Sun K, Wang Z, Ding H, Yuan J, Wei W, Hou Q, Wang H, Liu X, Zhang H, Ji Y, Zhou X, Sharma RK, Wang D, Ahmad F, Hui R, Song L.
Eur J Heart Fail.  2014; 16(9):950-7.
PMID: 25132132


Transgenic knockdown of cardiac sodium/glucose cotransporter 1 (SGLT1) attenuates PRKAG2 cardiomyopathy, whereas transgenic overexpression of cardiac SGLT1 causes pathologic hypertrophy and dysfunction in mice.
Ramratnam M, Sharma RK, D'Auria S, Lee SJ, Wang D, Huang XY, Ahmad F.
JAHA. 2014; 3(4).
PMID: 25092788 


Rare variants in genes encoding MuRF1 and MuRF2 are modifiers of hypertrophic cardiomyopathy.
Su M, Wang J, Kang L, Wang Y, Zou Y, Feng X, Wang D, Ahmad F, Zhou X, Hui R, Song L.
Int J Mol Sci. . 2014; 15(6):9302-13.
PMID: 24865491 


The genomic complexity underlying pulmonary arterial hypertension: from mendel to networks.
Rajkumar R, Ahmad F.
Am J Respir Crit Care Med. 2014; 189(10):1152-4.
PMID: 24832737 


Female sex is associated with worse prognosis in patients with hypertrophic cardiomyopathy in China.
Wang Y, Wang J, Zou Y, Bao J, Sun K, Zhu L, Tian T, Shen H, Zhou X, Ahmad F, Hui R, Song L.
PloS one. 2014; 9(7):e102969.
PMID: 25047602 


Cellular, pharmacological, and biophysical evaluation of explanted lungs from a patient with sickle cell disease and severe pulmonary arterial hypertension.
Rogers NM, Yao M, Sembrat J, George MP, Knupp H, Ross M, Sharifi-Sanjani M, Milosevic J, St Croix C, Rajkumar R, Frid MG, Hunter KS, Mazzaro L, Novelli EM, Stenmark KR, Gladwin MT, Ahmad F, Champion HC, Isenberg JS.
Pulm Circ. 2013; 3(4):936-51.
PMID: 25006410


High mobility group box 1 contributes to the pathogenesis of experimental pulmonary hypertension via activation of Toll-like receptor 4.
Bauer EM, Shapiro R, Zheng H, Ahmad F, Ishizawar D, Comhair SA, Erzurum SC, Billiar TR, Bauer PM.
Mol Med. 2013; 18:1509-18.
PMID: 23269975


Autosomal recessive transmission of MYBPC3 mutation results in malignant phenotype of hypertrophic cardiomyopathy.
Wang Y, Wang Z, Yang Q, Zou Y, Zhang H, Yan C, Feng X, Chen Y, Zhang Y, Wang J, Zhou X, Ahmad F, Hui R, Song L.
PloS one. 2013; 8(6):e67087.
PMID: 23840593 

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