Recent Publications

Li Z, Agrawal V, Ramratnam M, Sharma RK, D'Auria S, Sincoular A, Jakubiak M, Music ML, Kutschke WJ, Huang XN, Gifford L, Ahmad F. Cardiac sodium-dependent glucose cotransporter 1 is a novel mediator of ischaemia/reperfusion injury. Cardiovasc Res. 2019 Sep 1;115(11):1646-1658. doi: 10.1093/cvr/cvz037. PubMed PMID: 30715251; PubMed Central PMCID: PMC6704393.

Dieseldorff Jones KM, Koh Y, Weller RS, Turna RS, Ahmad F, Huke S, Knollmann BC, Pinto JR, Hwang HS. Pathogenic troponin T mutants with opposing effects on myofilament Ca(2+) sensitivity attenuate cardiomyopathy phenotypes in mice. Arch Biochem Biophys. 2019 Jan;661:125-131. doi: 10.1016/j.abb.2018.11.006. Epub 2018 Nov 13. PubMed PMID: 30445044; PubMed Central PMCID: PMC6347385. 

Polgreen PM, Brown GD, Hornick DB, Ahmad F, London B, Stoltz DA, Comellas AP. CFTR Heterozygotes Are at Increased Risk of Respiratory Infections: A Population-Based Study. Open Forum Infect Dis. 2018 Nov;5(11):ofy219. doi: 10.1093/ofid/ofy219. eCollection 2018 Nov. PubMed PMID: 30397620; PubMed Central PMCID: PMC6210382.

Ramratnam M, Salama G, Sharma RK, Wang DW, Smith SH, Banerjee SK, Huang XN, Gifford LM, Pruce ML, Gabris BE, Saba S, Shroff SG, Ahmad F. Gene-Targeted Mice with the Human Troponin T R141W Mutation Develop Dilated Cardiomyopathy with Calcium Desensitization. PloS one. 2016; 11(12):e0167681. PMID: 27936050

Wang J, Wang Y, Zou Y, Sun K, Wang Z, Ding H, Yuan J, Wei W, Hou Q, Wang H, Liu X, Zhang H, Ji Y, Zhou X, Sharma RK, Wang D, Ahmad F, Hui R, Song L. Malignant effects of multiple rare variants in sarcomere genes on the prognosis of patients with hypertrophic cardiomyopathy. Eur J Heart Fail.  2014; 16(9):950-7. PMID: 25132132

Ramratnam M, Sharma RK, D'Auria S, Lee SJ, Wang D, Huang XY, Ahmad F. Transgenic knockdown of cardiac sodium/glucose cotransporter 1 (SGLT1) attenuates PRKAG2 cardiomyopathy, whereas transgenic overexpression of cardiac SGLT1 causes pathologic hypertrophy and dysfunction in mice. JAHA. 2014; 3(4). PMID: 25092788

Su M, Wang J, Kang L, Wang Y, Zou Y, Feng X, Wang D, Ahmad F, Zhou X, Hui R, Song L. Rare variants in genes encoding MuRF1 and MuRF2 are modifiers of hypertrophic cardiomyopathy. Int J Mol Sci. . 2014; 15(6):9302-13. PMID: 24865491
 
Rajkumar R, Ahmad F. The genomic complexity underlying pulmonary arterial hypertension: from mendel to networks. Am J Respir Crit Care Med. 2014; 189(10):1152-4. PMID: 24832737

Wang Y, Wang J, Zou Y, Bao J, Sun K, Zhu L, Tian T, Shen H, Zhou X, Ahmad F, Hui R, Song L. Female sex is associated with worse prognosis in patients with hypertrophic cardiomyopathy in China. PloS one. 2014; 9(7):e102969. PMID: 25047602

Rogers NM, Yao M, Sembrat J, George MP, Knupp H, Ross M, Sharifi-Sanjani M, Milosevic J, St Croix C, Rajkumar R, Frid MG, Hunter KS, Mazzaro L, Novelli EM, Stenmark KR, Gladwin MT, Ahmad F, Champion HC, Isenberg JS. Cellular, pharmacological, and biophysical evaluation of explanted lungs from a patient with sickle cell disease and severe pulmonary arterial hypertension. Pulm Circ. 2013; 3(4):936-51. PMID: 25006410

Bauer EM, Shapiro R, Zheng H, Ahmad F, Ishizawar D, Comhair SA, Erzurum SC, Billiar TR, Bauer PM. High mobility group box 1 contributes to the pathogenesis of experimental pulmonary hypertension via activation of Toll-like receptor 4. Mol Med. 2013; 18:1509-18. PMID: 23269975

Wang Y, Wang Z, Yang Q, Zou Y, Zhang H, Yan C, Feng X, Chen Y, Zhang Y, Wang J, Zhou X, Ahmad F, Hui R, Song L. Autosomal recessive transmission of MYBPC3 mutation results in malignant phenotype of hypertrophic cardiomyopathy. PloS one. 2013; 8(6):e67087. PMID: 23840593